白介素12(IL12)單克隆抗體
Monoclonal Antibody to Interleukin 12 (IL12)
p70
- 編號UMAA111Hu21
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(jià)(克隆號)C5
- Ig亞型 IgG2bKappa
- 純化方式蛋白A + 蛋白G親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原 EPA111Hu62-白介素12(IL12)真核蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度1mg/mL
- 且適物種Rattus norvegicus (Rat，大鼠)
- 應(yīng)用WB
如果抗體需用于流式細(xì)胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價(jià)格 ¥ 306 ¥ 714 ¥ 1020 ¥ 2550 ¥ 10200
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Western Blot; Samples: Lane1: Rat Spleen cells treated with 25ng/ml LPS and 10μg/ml PHA for 48 hours, cell supernatant; Lane2: Untreated Rat Spleen lysate;
Primary Ab: 0.5μg/ml Mouse Anti-Human IL12 Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對IL12的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識別IL12。
用法
Western blotting: 0.01-2μg/mL;
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| UAPA111Hu62 | 白介素12(IL12)活性蛋白 | Cell?culture;?Activity?Assays. |
| UEPA111Hu62 | 白介素12(IL12)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA111Hu61 | 白介素12(IL12)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UAPA111Hu61 | 白介素12(IL12)活性蛋白 | Cell?culture;?Activity?Assays. |
| UMAA111Hu22 | 白介素12(IL12)單克隆抗體 | WB |
| UMAA111Hu21 | 白介素12(IL12)單克隆抗體 | WB |
| USEA111Hu | 白介素12(IL12)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| UMEA111Hu | 白介素12(IL12)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| UAEA111Hu | 抗白介素12抗體(Anti-IL12)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antibody Detection. |
| USCA111Hu | 白介素12(IL12)檢測試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA111Hu | 白介素12(IL12)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Journal?of?Virology | Characterization?of?Simian?Immunodeficiency?Virus?Variants?Anatomically?Compartmentalized?inPlasma?and?Milk?in?Chronically?Infected?African?Green?Monkeys. [pubmed:] |
| Cancer?Science | A Novel Potential Strategy for Enhancing Antigen Presentation of Human Hepatocellular Carcinoma Cells Propagated ex-vivo Using a Ribonuclease Enzyme?… [Scholarena:Source] |
| International Immunopharmacology | Switched memory B cells promote alveolar bone damage during periodontitis: An adoptive transfer experiment [Pubmed:30015235] |
| Oncology?Letters | Antitumor efficacy of the Runx2?dendritic cell vaccine in triple?negative breast cancer in vitro [Pubmed:30127867] |
| Neuroscience | The P2X7 receptor, cathepsin S and fractalkine in the trigeminal subnucleus caudalis signal persistent hypernociception in temporomandibular rat joints [Pubmed: 30248434] |
| Cancer?Biomarkers | Soluble LAG3 acts as a potential prognostic marker of gastric cancer and its positive correlation with CD8+ T cell frequency and secretion of IL-12 and INF-γ in?… [Pubmed: 30223387] |
| International?Journal?of?Clinical?and?Experimental?Medicine | The relationship between autophagy and apoptosis of lamina propria dendritic cells from the small intestine on the immunodynamics of sepsis mice [] |
| ВЛИЯНИЕ ДНК МЕТИЛТРАНСФЕРАЗЫ 3А И ГИСТОНДЕАЦЕТИЛАЗЫ НА СОДЕРЖАНИЕ В МОНОНУКЛЕАРНЫХ КЛЕТКАХ ЦЕЛЬНОЙ КРОВИ?… [] | |
| Experimental and Therapeutic Medicine | RBP and Alb in neonatal hydronephrosis and its association with IL-12 levels in pregnant women before delivery [] |
| Chemosphere | Atmospheric H2S triggers immune damage by activating the TLR-7/MyD88/NF-κB pathway and NLRP3 inflammasome in broiler thymus [] |
| Infection and Drug Resistance | Disseminated And Infection Accompanied Sweet's Syndrome In A Patient With Anti-Interferon-γ Autoantibodies: A Case Report. [Pubmed: 31632104] |
| Biomed Pharmacother | Suppression of Fpr2 expression protects against endotoxin-induced acute lung injury by interacting with Nrf2-regulated TAK1 activation [Pubmed: 32106380] |
| Silkworm pupa oil attenuates acetaminophen‐induced acute liver injury by inhibiting oxidative stress‐mediated NF‐κB signaling [Pubmed: 31993149] | |
| J Vet Med Sci | Innate immune response of mammary gland induced by intramammary infusion of Bifidobacterium breve in lactating dairy cows [Pubmed: 33071254] |
| Bat? Karadeniz T?p Dergisi | Vasküler Demans Modelinde ?evresel Zenginle?tirmenin Depresyon Benzeri Davran??, Kortikal ve Hipokampal BDNF ve IL-1β Seviyeleri üzerine Etkisi [] |
| Evaluation of lipopolysaccharide-induced acute lung injury attenuation in mice by Glycyrrhiza glabra [] | |
| Life Sci | BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-|êB signaling in DSS-induced colitis in rats [33548287] |
| IUBMB Life | HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1 [34117711] |
| Int J Biol Macromol | Establishing novel roles of bifidocin LHA, antibacterial, antibiofilm and immunomodulator against Pseudomonas aeruginosa corneal infection model [34171261] |
| Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma [34377237] |
| J Periodontol | Cytokine profile in serum and gingival crevicular fluid of children with inflammatory bowel disease: A case‐control study [34730850] |
| Biomedicines | Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes [34829910] |
| Journal of Nanobiotechnology | Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM [Pubmed:35351131] |
| J Nanobiotechnology | Cyclosporine A loaded brain targeting nanoparticle to treat cerebral ischemia/reperfusion injury in mice [Pubmed:35658867] |
| Biomedicines | Deletion of Toxoplasma Rhoptry Protein 38 (PruΔrop38) as a Vaccine Candidate for Toxoplasmosis in a Murine Model [Pubmed:35740356] |
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