基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體(異硫氰酸熒光素標(biāo)記)
FITC-Linked Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)
CLG3; Collagenase 3
- 編號ULAA099Rb81
- 物種Oryctolagus cuniculus (Rabbit，兔) 相同的名稱，不同的物種。
- 來源抗體標(biāo)記
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物熒光素
- 原抗體 PAA099Rb51-基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度500μg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC; IF.
如果抗體需用于流式細(xì)胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 430 ¥ 1004 ¥ 1434 ¥ 3585 ¥ 14340
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對MMP13的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗中能識別MMP13。
用法
Western blotting: 0.5-2μg/mL
Immunohistochemistry: 5-20μg/mL
Immunocytochemistry: 5-20μg/mL
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Oryctolagus cuniculus (Rabbit，兔) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA099Rb01 | 基質(zhì)金屬蛋白酶13(MMP13)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA099Rb03 | 基質(zhì)金屬蛋白酶13(MMP13)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA099Rb02 | 基質(zhì)金屬蛋白酶13(MMP13)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA099Rb53 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAA099Rb01 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAA099Rb02 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAA099Rb51 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 | ICC/IF |
| UPAA099Rb52 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 | WB; IHC; ICC; IP. |
| ULAA099Rb81 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| ULAA099Rb71 | 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| USEA099Rb | 基質(zhì)金屬蛋白酶13(MMP13)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCA099Rb | 基質(zhì)金屬蛋白酶13(MMP13)檢測試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA099Rb | 基質(zhì)金屬蛋白酶13(MMP13)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
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| PLoS ONE | A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches [Plosone: Source] |
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| International Journal of Contemporary Medical Research | Matrix Metalloproteinase-13 (MMP-13): A Novel Tumor Marker for Diagnosis of Breast Carcinoma [uploads:7] |
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| Molecular Medicine Reports | Icariin inhibits MMP?1, MMP?3 and MMP?13 expression through MAPK pathways in IL?1β?stimulated SW1353 chondrosarcoma cells [pubmed:28447732] |
| bmc musculoskeletal disorders | Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis. [pubmed:28187731] |
| Journal of Cellular Physiology | Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Models [pubmed:27739057] |
| BMC Musculoskeletal Disorders | Establishment of rat ankle post-traumatic osteoarthritis model induced by malleolus fracture [pubmed:29149841] |
| Journal of Applied Animal Research | Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts:an in vitro approach to bovine digital dermatitis [10.108:09712119.2017.1335208] |
| Alexandria Journal of Medicine | L-Carnitine ameliorates knee lesions in mono-iodoacetate induced osteoarthritis in rats [10.1016:j.ajme.2016.03.002] |
| National Journal of Integrated Research in Medicine | Matrix Metalloproteinase-13 Can Be Used As an Independent Diagnostic and Prognostic Marker for Breast Carcinoma. [AN=123116960] |
| Molecular?Medicine?Reports | Effects of GGCX overexpression on anterior cruciate ligament transection-induced osteoarthritis in rabbits [Pubmed:29257344] |
| Journal of Applied Animal Research? | Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts: an approach to bovine digital dermatitis [10.1080:09712119.2017.1335208] |
| Osteoarthritis Cartilage | Coordinated existence of multiple gangliosides is required for cartilage metabolism [Pubmed: 30471358] |
| PLoS One | Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis [Pubmed: 30939166] |
| Pathobiology | Suppressed Expression but Not Activity of Collagenases MMP-1 and MMP-13 in Human Renal Carcinoma [Pubmed: 31129674] |
| Bone | DAla2GIP antagonizes H2O2-induced chondrocyte apoptosis and inflammatory factor secretion [Pubmed: 31283994] |
| Food & Function | A dietary polysaccharide from Eucheuma cottonii downregulates proinflammatory cytokines and ameliorates osteoarthritis-associated cartilage degradation in obese?… [] |
| JOURNAL OF CELLULAR BIOCHEMISTRY | Teneligliptin inhibits IL‐1β‐induced degradation of extracellular matrix in human chondrocytes [Pubmed: 32162384] |
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| Scientific Reports | Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis [Pubmed: 31980722] |
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| Nature Communications | Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13 [Pubmed: 32807790] |
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| Hyaluronic Acid versus Alpha-2-Macroglobulin Intra-Articular Injections for Amelioration of Knee Posttraumatic Osteoarthritis: A Rat Model [] | |
| Loss of autophagy in tibial plateau chondrocytes causes increased apoptosis of chondrocytes in spontaneous osteoarthritis of guinea pigs [] | |
| Food Funct | Undenatured type II collagen prevents and treats the osteoarthritis and motor function degradation in T2DM patients and db/db mice [33890588] |
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| Sci Rep | Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis [Pubmed:35091584] |
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