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Gremlin 1蛋白(GREM1)多克隆抗體

Polyclonal Antibody to Gremlin 1 (GREM1)

PIG2; CKTSF1B1; DAND2; IHG-2; DAND2; DRM; Increased in high glucose protein 2; Cell proliferation-inducing gene 2 protein; Cysteine knot superfamily 1, BMP antagonist 1

編號(hào)UPAC128Hu01
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來(lái)源多抗制備
宿主兔
效價(jià)-
Ig類型 IgG
純化方式抗原特異性親和純化
標(biāo)記物無(wú)標(biāo)記物
免疫原 RPC128Hu01-Gremlin 1蛋白(GREM1)重組蛋白
緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
性狀液體
濃度0.5mg/mL
且適物種Rattus norvegicus (Rat，大鼠)
應(yīng)用WB; IHC
如果抗體需用于流式細(xì)胞術(shù)，請(qǐng)參見(jiàn)流式抗體。
下載英文說(shuō)明書中文說(shuō)明書
規(guī)格 20μl100μl 200μl 1ml 10ml
價(jià)格 ¥ 315 735 ¥ 735 ¥ 1050 ¥ 2625 ¥ 10500
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

DAB staining on IHC-P; Samples: Rat Intestine Tissue; Primary Ab: 20μg/ml Rabbit Anti-Human GREM1 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
DAB staining on IHC-P;
Samples: Human Kidney Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Human GREM1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
DAB staining on IHC-P;
Samples: Human Testis Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Human GREM1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)

Figure. Western Blot; Sample: Recombinant GREM1, Human.

通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對(duì)GREM1的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別GREM1。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

增值服務(wù)

抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
 細(xì)胞和組織染色液
 抗體陽(yáng)性對(duì)照品
 組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
 DAB顯色試劑盒
 SABC試劑盒
 長(zhǎng)臂生物素標(biāo)記試劑盒
 實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Lung	Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension [PubMed: 25926293]
Tumour Biol	Overexpression of Gremlin promotes non-small cell lung cancer progression [PubMed: 26392110]
Int J Cardiol	Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-term prognosis in suspected and proven acute heart failure patients [PubMed: 26539964]
International Journal of Cardiology	Triple?head-to-head?comparison?of?fibrotic?biomarkers?galectin-3,?osteopontin?and?gremlin-1?for?long-termprognosis?in?suspected?and?proven?acute?heart?failure?patients [Pubmed:26539964]
American Journal of Respiratory Cell and Molecular Biology	BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH [Pubmed:27187737]
J Rheumatol	GREM1 Is a Key ReCavia (Guinea pig )lator of Synoviocyte Hyperplasia and Invasiveness [Pubmed:26834210]
European cells & materials	The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. [pubmed:28266688]
Sci Rep.	Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients. [pubmed:28327551]
American Journal of Respiratory Cell and Molecular Biology	Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial … [rcmb.2015-0402OC]
Molecular Medicine Reports	Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells [pubmed:28260028]
Cellular Haemostasis and Platelets	Platelets as a novel source of Gremlin-1: Implications for thrombo inflammation [pubmed:27929199]
Scientific Reports	Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis [Pubmed: 31053735]
International Journal of Molecular Sciences	Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration [Pubmed: 31878307]
American Journal of Physiology-Cell Physiology	Suppression of microRNA-23a/b-3p delays the development degenerative joint disease by activating Grem1 and TGF-β/Smad signaling pathway [Pubmed: 32186934]
Inflammopharmacology	Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa [Pubmed:35441352]
Mol Carcinog	CAF‐derived exosomes transmitted Gremlin‐1 promotes cancer progression and decreases the sensitivity of hepatoma cells to sorafenib [Pubmed:35638711]

留言咨詢

編號(hào)	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
UAPC128Hu02	Gremlin 1蛋白(GREM1)活性蛋白	Cell?culture;?Activity?Assays.
URPC128Hu01	Gremlin 1蛋白(GREM1)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
UAPC128Hu01	Gremlin 1蛋白(GREM1)活性蛋白	Cell?culture;?Activity?Assays.
URPC128Hu02	Gremlin 1蛋白(GREM1)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
UPAC128Hu01	Gremlin 1蛋白(GREM1)多克隆抗體	WB; IHC
UPAC128Hu02	Gremlin 1蛋白(GREM1)多克隆抗體	WB; IHC
ULAC128Hu81	Gremlin 1蛋白(GREM1)多克隆抗體(異硫氰酸熒光素標(biāo)記)	WB; IHC; ICC; IF.
ULAC128Hu71	Gremlin 1蛋白(GREM1)多克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
UMAC128Hu21	Gremlin 1蛋白(GREM1)單克隆抗體	IHC
UMAC128Hu23	Gremlin 1蛋白(GREM1)單克隆抗體	IHC
URAC128Hu21	Gremlin 1蛋白(GREM1)重組抗體	WB; IF; ICC; IHC; IP; FCM.
UMAC128Hu22	Gremlin 1蛋白(GREM1)單克隆抗體	IHC
USEC128Hu	Gremlin 1蛋白(GREM1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
ULMC128Hu	Gremlin 1蛋白(GREM1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.